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101.
102.
Concluding the Amyloid Formation Pathway of a Coiled‐Coil‐Based Peptide from the Size of the Critical Nucleus 下载免费PDF全文
Dr. Ulla I. M. Gerling Dr. Markus S. Miettinen Prof. Dr. Beate Koksch 《Chemphyschem》2015,16(1):108-114
The size of the critical nucleus acting as intermediate in the amyloid formation of a model peptide is calculated. The theoretical approach is based on experimentally determined amyloid formation rates and gives new insights into the amyloid formation pathway. 相似文献
103.
Numerical Comparison of Some Penalty-Based Constraint Handling Techniques in Genetic Algorithms 总被引:1,自引:0,他引:1
We study five penalty function-based constraint handling techniques to be used with genetic algorithms in global optimization. Three of them, the method of superiority of feasible points, the method of parameter free penalties and the method of adaptive penalties have already been considered in the literature. In addition, we introduce two new modifications of these methods. We compare all the five methods numerically in 33 test problems and report and analyze the results obtained in terms of accuracy, efficiency and reliability. The method of adaptive penalties turned out to be most efficient while the method of parameter free penalties was the most reliable. 相似文献
104.
Interactive Solution Approach to a Multiobjective Optimization Problem in a Paper Machine Headbox Design 总被引:1,自引:0,他引:1
J.P. Hämäläinen K. Miettinen P. Tarvainen J. Toivanen 《Journal of Optimization Theory and Applications》2003,116(2):265-281
A successful application of the interactive multiobjective optimization method NIMBUS to a design problem in papermaking technology is described. Namely, an optimal shape design problem related to the paper machine headbox is studied. First, the NIMBUS method, the numerical headbox model, and the associated multiobjective optimization problem are described. Then, the results of numerical experiments are presented. 相似文献
105.
The new signature scheme presented by the authors in [13] is the first signature scheme based on the discrete logarithm problem that gives message recovery. The purpose of this paper is to show that the message recovery feature is independent of the choice of the signature equation and that all ElGamal-type schemes have variants giving message recovery. For each of the six basic ElGamal-type signature equations five variants are presented with different properties regarding message recovery, length of commitment and strong equivalence. Moreover, the six basic signature schemes have different properties regarding security and implementation. It turns out that the scheme proposed in [13] is the only inversionless scheme whereas the message recovery variant of the DSA requires computing of inverses in both generation and verification of signatures. In general, message recovery variants can be given for ElGamal-type signature schemes over any group with large cyclic subgroup as the multiplicative group of GF(2n) or elliptic curve over a finite field.The present paper also shows how to integrate the DLP-based message recovery schemes with secret session key establishment and ElGamal encryption. In particular, it is shown that with DLP-based schemes the same functionality as with RSA can be obtained. However, the schemes are not as elegant as RSA in the sense that the signature (verification) function cannot at the same time be used as the decipherment (encipherment) function. 相似文献
106.
Abstract The aim of this study was to compare three different test methods for assaying the biodegradability of starch-based materials. The materials tested included some commercial starch-based materials and thermoplastic starch film prepared by extrusion from native potato starch and glycerol. Enzymatic hydrolysis was performed using excess Bacillus licheniformis α-amylase and Aspergillus niger glucoamylase at 37°C. The degree of degradation was assayed by measuring the dissolved carbohydrates and the weight loss of the samples. The head-space test was based on carbon dioxide evolution using sewage sludge as an inoculum. The composting experiments were carried out in an insulated commercial composter bin. The degradation was evaluated visually at weekly intervals, and the weight loss of the samples was measured after composting. Good correlation was found among the three different test methods. 相似文献
107.
Helttunen K Moridi N Shahgaldian P Nissinen M 《Organic & biomolecular chemistry》2012,10(10):2019-2025
Silver complexes of a cation binding supramolecular host, resorcinarene bis-crown (CNBC5) with propyl, nonyl, decyl and undecyl alkyl chains were investigated by NMR titration, picrate extraction and single crystal X-ray diffraction. Binding studies showed that both 1 : 1 and 1 : 2 (host-Ag(+)) complexes are present in solution with only a slight effect of the lower rim alkyl chain length on the binding constants (log K 4.0-4.2 for 1 : 2 complexes). Solid state complexes of the resorcinarene bis-crowns bearing either C(3) or C(11) chains were obtained. Single crystal X-ray analyses showed that both derivatives bind silver ions by metal-arene and Ag···O coordination from the crown ether bridges and from the solvent, and pack in layered or bilayered fashion. Furthermore, the amphiphilic nature of C11BC5 was demonstrated using the Langmuir balance technique. Langmuir-Blodgett films of the amphiphilic C11BC5-Ag complex were transferred onto a substrate and shown to possess antibacterial activity against E. coli. 相似文献
108.
109.
Unitarity in the s-channel is invoked to derive an upper bound for the inelastic diffractive cross-section as a function of impact parameter. The application of this bound to high-energy proton-proton scattering strongly suggests that inelastic diffraction should be peripheral in the impact parameter space. 相似文献
110.
In this paper we consider semilinear parabolic boundary value problems having nonsmooth and nonmonotone behaviour and memory effects. The mathematical problem can be formulated and studied by using the notions of hemivariational inequality (based on the generalized gradient in the sense of F.H. Clarke) and the hysteresis operator. We establish two general existence results for such problems. Applications from mechanics illustrate the theory. 相似文献